Tried to check if I can see what profile it loads / uses.
When clicking a link in an external application it loads like this:

c:\ironportable\iron.exe --
www.nu.nl
When normally opening the application it loads:

c:\ironportable\iron.exe -user-data-dir=c:\ironportable\profile
So, it seems that it looks for the "normal" location of the proile and not the portable location.
Checked this by putting my profile into the folder [C:\Users\myname\AppData\Local\Chromium\User Data] this causes the profile to load properly even when opening it by clicking a link in the external application.
This should confirms that the portable application only works if you always open it with a definition of the alternate user profile location.
Again..... anyone able to confirm that this needs to be reported here
